European RIs vs COVID-19
We are currently experiencing a public health crisis unprecedented in the modern European history of the last decades. As thousands of European citizens are infected with the SARS-CoV-2 every day and the number of casualties is increasing rapidly, Europe needs a coordinated effort of all available knowledge and resources to fight the pandemic.
ESFRI believes that the opportunities provided by European Research Infrastructures to support the science-led response to the COVID-19 outbreak are extremely important. ESFRI is helping the scientific community by aggregating information about dedicated services offered by Research Infrastructures and communicating all relevant actions as broadly as possible. To this end, ESFRI has created this focused webpage that lists and provides quick links to the information gathered.
This page will be updated regularly, as more information becomes available from all over Europe. We would like also like to invite all national & European Research Infrastructures to provide any information on their COVID-19 related activities and services in order to be added to this page.
Please use firstname.lastname@example.org and email@example.com for any communication.
ESFRI Chair, Jan Hrusak, and the Executive Board of the Forum would like to express their sincere thanks to all Research Infrastructures for their eager response to this urgent call for information and for their overall motivation to provide their best services for this fight.
#ERAvsCorona Action Plan
This ESFRI initiative feeds into a larger set of coordinated R&I actions at EU level presented in the ERA vs. Corona Action Plan. The Action Plan sets out key measures to coordinate, share, and increase support for R&I.
In particular, for Research Infrastructures, funds are being added and re-oriented to support RI projects providing services and activities in response to the Coronavirus outbreak. In order to share research data, a European data exchange platform for Coronavirus is also being established in the framework of the European Open Science Cloud.
COVID-19 Services & Resources
ACTRIS: Air quality and atmospheric composition data
The European RI for the observation of Aerosol, Clouds and Trace Gases (ACTRIS) provides virtual access to the near-real time data on air quality and atmospheric composition. This is of particular interest and importance as it provides with an unprecedented overview of the European air quality and atmospheric composition during the lockdown. The near-real time data are open access and available through the ACTRIS Data Centre upon request/special data policy.
Alliance of Medical Research Infrastructures
The COVID-19 Fast Response Service is a coordinated and accelerated procedure for researchers to access the academic facilities, services and resources of the three medical research infrastructures: the European Research Infrastructure for Translational Medicine (EATRIS), the European Clinical Research Infrastructure network (ECRIN) and the European research infrastructure for biobanking (BBMRI), working together under the umbrella of the Alliance of Medical Research Infrastructures (AMRI).
CERIC-ERIC: Access to selected instruments
In order to facilitate the research on the COVID-19, CERIC has set up a dedicated Fast Track Access to a selected number of instruments. The dedicated Fast Track Access will allow to access the selected instruments for research related to the COVID-19, without the necessity to undergo the regular evaluation procedure, and be scheduled within one month from the submission of the proposal, based on the feasibility evaluation performed by the facility.
CERN Against COVID-19 initiative
The objective of the CERN against COVID-19 initiative is to ensure effective and well-coordinated action, drawing on CERN’s many competencies and advanced technologies and working closely with experts in healthcare, drug development, epidemiology and emergency response so as to maximise the impact of CERN contributions. CERN is focusing these efforts in three action areas:
- Medical applications: design and production of medical supplies and equipment, ranging from producing sanitiser gel, to developing full-scale ventilators for use in hospitals.
- Computing and data analysis: the vast global computing resource, Worldwide LHC Computing Grid, (WLCG), and CERN openlab collaboration can provide considerable resources for fighting the pandemic.
- Help to society: emergency response teams available to support local ambulance services, donations of PPE, production of Perspex barriers to protect those working in public services.
CESSDA: Social research data and analysis tools
The Consortium of European Social Science Data Archives (CESSDA) is a distributed social data research infrastructure providing a European Data Catalogue, data facilities at national Service Providers to archive, curate and access research data, and tools for experts: Controlled Vocabularies Manager, European Multilingual Thesaurus, European Question Bank. COVID-related topics in social data include social behaviour, work, health, travel, social norms & values, attitudes toward government measures, vaccination, etc.
CETAF and DiSSCo: Joint COVID-19 Task Force
The Consortium of European Taxonomic Facilities (CETAF) and the Distributed System of Scientific Collections (DiSSCo) are forming a covid-19 Task Force. The Task Force will bring together experts with background in topics relevant to the key aspects for the understanding of the zoonotic nature of the SARS-Cov-2 and contribute to the global efforts from the perspective of both key biological properties of the virus and biological informatics. The Task Force objectives are focused on (a) expediting processes across DiSSCo facilities related to the implementation of covid-19 projects, (b) mobilising ad-hoc data across the 120 museums and the more than 1 billion biological specimens and (c) facilitating access to laboratory equipment for analysis of relevant material.
CLARIN: Multilingual research data and tools
In light of the COVID-19 pandemic, the Common Language Resources and Technology Infrastructure (CLARIN) provides new research resources. One of the actions currently being prepared is a campaign aimed at extending the curated collections of parliamentary data sets from all over Europe with the records of recent debates on the Corona dynamics. The enhanced data can be the basis for comparative research into the ways in which public bodies have responded to the crisis across countries. Additionally, CLARIN will focus on supporting the development of tools for detecting mis- and disinformation to be applied to news sources and social media platforms. The uniqueness of these resources is that they are available in all European languages, allowing a multilingual approach to COVID-19 related research.
DARIAH: Open call for proposals
DARIAH is launching a call for proposals under the bi-annual DARIAH Theme funding scheme that will seek specific responses to the pandemic that engage arts and humanities sources, approaches and insight, to ensure that research across all topics and areas in our community can continue. One of the areas of emphasis in this scheme will be on how we will collect, curate, preserve and interpret the heterogenous record of the experience of life and work in early 2020.
EATRIS: Biomedical research resources
The research resources of European Infrastructure for Translational Medicine (EATRIS) are highly relevant for the research community in the context of the COVID-19 pandemic, and has created an inventory of all related research activities underway at EATRIS facilities.
As part of the Alliance of Medical Infrastructures with BBMRI and ECRIN, EATRIS also offers a Fast Response Service for researchers.
ECRIN: Fast-track access to clinical study support
The European Clinical Research Infrastructure (ECRIN) provides support to the planning and design of multinational clinical studies, and operational services to the management of the trial. In the COVID-19 context, ECRIN develops a fast-track procedure for access to, and provision of services. After supporting investigators and sponsors in designing and planning the trial (including on the regulatory and ethical context), ECRIN provides operational support to the sponsors for the management of the multinational trial, including ethical, regulatory and data protection approvals, vigilance, data monitoring anddata management services (through ECRIN-certified data centres).
As part of the Alliance of Medical Infrastructures with BBMRI and EATRIS, ECRIN also offers a Fast Response Service for researchers.
EGI: HADDOCK, a biomolecular simulations platform
HADDOCK (High Ambiguity Driven protein-protein DOCKing) is an integrative platform developed at Utrecht University for the modelling of biomolecular complexes and is one of the WeNMR thematic services. HADDOCK can support complex simulation projects, and benefits from the distributed computing infrastructure of EGI. In the context of COVID-19 related research it can, for example, model interaction between virus proteins and human one, or support the docking of small molecules to targets such as the COVID-19 protease. The tool is offered by the Bijvoet Center of the Utrecht University, Netherlands, is supported by the EOSC-hub H2020 project and is also accessible through the European Open Science Cloud Portal.
ELIXIR: Life science data tools and resources
ELIXIR, the ESFRI Research Infrastructure for life science data, provides a range of services and resources, that can be used by researchers and consortia working on SARS-CoV-2 research via ELIXIR Nodes. ELIXIR has also initiated new community-driven initiatives (e.g. Hackathons) that help to open up and link COVID-19 data. As details become available, they will be published on the ELIXIR COVID-19 webpage linked below.
eLTER: Socio-ecological implications of COVID-19
eLTER RI, in response to COVID-19 crisis, aims to utilize its network of socio-ecological research platforms (LTSER Platforms) and their teams to consider the characteristics of diverse geographic regions that will likely be important during the period of recovery and adaptation to new post-pandemic social, economic and environmental realities. Moreover, will utilize the capacity and infrastructure to monitor short to long term impacts of the socio-economic impacts of policy responses to COVID-19 on water/soil/air quality, ecosystem functioning and ecosystem services, to answer crucial pandemic-related questions such as whether there will be a long term effect of this pandemic on securing food production and other life-supporting ecosystem services.
EMBL-EBI: Biomedical data resources
In response to the current outbreak of COVID-19, EMBL-EBI is gathering and sharing data resources as they become available. Researchers can now see a breakdown of relevant data hosted at EMBL-EBI on the Pathogen Portal. This includes sequences of outbreak isolates and records relating to coronavirus biology. Researchers can also find instructions for submitting data to the European Nucleotide Archive (ENA). EMBL has recognised the urgency to identify and consolidate needs around creating a European COVID-19 Data Platform for data/information exchange, connected to the European Open Science Cloud (EOSC.
ERINHA: High containment facilities for pre-clinical research
The European Research Infrastructure on Highly Pathogenic Agents (ERINHA) provides access to its members – leading European high containment facilities (BSL3 and BSL4) -, as well as expertise and project management services to advance research on SARS-CoV-2 / COVID-19. The available high containment research capacities include: in vitro research capacity (standard virologic assays, high throughput SARS-CoV-2 screening assays, diagnostic development and testing capacity, virus propagation and quantification), in vivo research capacity (small animal disease models, Non-Human Primates (NHP) disease models, standard in vivo virologic and immunological assays, pre-clinical vaccines and therapeutics testing). Additionally ERINHA provides support for coordination of pre-clinical research activities, project management and advise on protocols.
ESRF-EBS: Priority access to bio-imaging and structural biology facilities
The European Synchrotron Radiation Facility Extremely Brilliant Source (ESRF-EBS), in collaboration with its EPN Science campus partners, ILL, EMBL, IBS, is ready to provide access to a unique combination of state-of-the-art facilities and common platforms for structural biology and bio-imaging for COVID-19 related research projects. This exceptional access will be granted with the aim to contribute to the international scientific effort to overcome the COVID-19 pandemic, and the available facilities include its cryo-electron microscope and its structural biology beamlines.
ESS-DEMAX: Priority access
The European Spallation Source (ESS) Deuteration and Macromolecular Crystallisation Support Lab, DEMAX, is already functioning on a small scale and we can provide expertise, advice, and limited materials to support research to address the critical need to understand and shut down the coronavirus disease, COVID-19. ESS will prioritise requests for the production of deuterated proteins, DNA, and some types of small molecules such as detergents and lipids that are all potentially useful for neutron scattering studies of viral components. In addition, as experienced scientists in small angle scattering, chemistry, structural biology, reflectometry, and crystallography we can also assist with structural modeling and data analysis.
ESS: Using survey data to understand the crisis
European Social Survey data collected in up to 38 countries across Europe every two years since 2002 remains freely available for anyone to access and analyse. In particular, consideration of responses to survey questions on happiness, loneliness, social relationships, health and wellbeing as well as trust in other people, government and institutions (including health services) is helpful for providing some context to the COVID-19 pandemic. Additionally, 20 items asking people specifically about Coronavirus will be included in the ESS Round 10 (2020/21) questionnaire. Half of these questions will be selected for inclusion following a call for proposals open to all academics and researchers.
EU-OPENSCREEN: Access to pilot compound library
EU-OPENSCREEN and its partner sites are actively involved in the study of SARS-CoV-2, aiming to identify therapeutics and search for diagnostics. EU-OPENSCREEN provides a fast access track for scientist wishing to use their pilot compound library for their COVID-19 related research activities.
Euro-BioImaging: Open access to services
Biological and biomedical imaging technologies are essential for addressing many of the research questions related to Covid-19, from fundamental research at the molecular and cellular level to medical applications and diagnostics. Euro-BioImaging ERIC provides open access to imaging technologies, training and data services at its 21 Nodes, listed in a dedicated web page along with other related resources.
EVAg: Development of SARS-Cov-2 diagnostic test
The European Virus Archive (EVA-Global) is a virtual collection for human, animal and plant viruses, that provides researchers with the necessary material for diagnosing Coronavirus infection. EVAg has developed, and published on January 21st, 2020, the now worldwide used PCR based SARS-Cov-2 diagnostic test. To date, more than 1000 kits of reagents and reference materials have been delivered worldwide, using EVAg budget provisions.
ILL: Rapid access to beam time
The Institut Laue-Langevin (ILL), plans to run 2 more cycles in 2020 which will constitute a significant opportunity to perform early research related to Covid-19 on many of our neutron scattering instruments. In addition to the instruments, there is access to deuteration facilities and shared biology and soft matter facilities with partner institutes on the EPN campus - the ESRF, EMBL and IBS. For rapid access to beam time, Director's Discretionary Time (for full experiments) and Easy Access (for short measurements) should be used.
INFRAFRONTIER: Model mammalian genome resources
INFRAFRONTIER has created a dedicated webpage listing all its specific resources and services for COVID-19 research. This site also lists the INFRAFRONTIER nodes that offer emergency archiving of mouse lines for laboratories that cannot maintain their colonies due to the coronavirus crisis.
Instruct-ERIC: Priority access to structural biology services
Instruct-ERIC is offering priority access to its structural biology services for research directly related to COVID-19. Priority access ensures a faster review of research proposals relating to COVID-19. In order to protect staff and users, physical visits to Instruct Centres have been suspended but it may be possible to undertake research remotely during the restricted access period, subject to individual Centre availability. In addition, Instruct-ERIC has compiled a list of resources for COVID-19 research, which may be of interest to the wider life science community. For enquiries relating to Instruct-ERIC services during the restricted access period, please contact the support office.
LIFEWATCH: Epidemiology and data support
In response to the COVID-19 pandemic, LIFEWATCH ERIC has planned an initiative where a group of international scientists with long-track experience in machine learning and modeling, which will join efforts to:
- Implement a large set of scenario and model simulations to establish alternative trajectories of spread for SARS-CoV-2
- Perform an extensive sensitivity analysis to understand the major sources of uncertainty associated with model projections
- Develop an on-line decision support system platform enabling individuals and stakeholders in the public and private sectors to query about risks in specific locations and time periods
- Support the federation, provenance and accountability mechanisms associated to distributed (e-)Resources (databases, publications, media, software, etc.) through Blockchain-based technologies.
METROFOOD-RI: Data on food & COVID-19
METROFOOD-RI, the Infrastructure for promoting Metrology in Food and Nutrition, has created a dedicated page with an organised and continuously updated collection on the official information, research findings, risk assessment and monitoring results related to food & COVID-19, with reference to the whole food chain, from primary production to final consumption.
NFFA-Europe: Fast track access to nanoscience facilities
NFFA-Europe offers the opportunity of submitting COVID-track proposals that will be assessed for feasibility and peer-evaluated one by one for Remote Transnational Access. COVID-track proposals may require access to all facilities for nanofabrication and nanoscale analysis on materials, nano-delivery systems of vaccins, models, numerical simulations or any directly relevant research that may need urgent access to NFFA-Europe resources.
PRACE: Access to computing resources
PRACE (Partnership for Advanced Computing in Europe) is welcoming project proposals requesting computing resources to contribute to the mitigation of the impact of the COVID-19 pandemic. PRACE partners, HPC centres, and research infrastructures are doing their bit by opening up their facilities for urgent/priority access to the HPC systems and other resources to support the research to combat the coronavirus. Please find a list of these initiatives here.
SHARE: Data on Europe’s older risk population
The Survey of Health, Ageing and Retirement in Europe (SHARE) is ideally suited to examine how the high-risk group of the older individuals is coping with the health-related and socioeconomic impact of COVID-19. SHARE provides a multidisciplinary and cross-national panel database on the health and socioeconomic living conditions of about 140,000 individuals aged 50 or older in 27 European countries and Israel, and this every two years since 2004. SHARE is embedded in a worldwide network of harmonized ageing surveys. Hence, SHARE permits European and even worldwide comparisons of how well the healthcare and social systems have responded to the pandemic and which lessons should be drawn for the future.
TRANSVAC2: Support for COVID-19 vaccine development
TRANSVAC2 has redirected the currently open call to focus on SARS-Cov2 vaccine efforts. Researchers developing vaccine candidates against COVID-19 are encouraged to apply and benefit from all TRANSVAC2 services, such as:
- Adjuvant formulation (Vaccine Formulation Institute and Helmholtz Centre for Infection Research)
- Structural Biology (INSTRUCT)
- Animal models (CEA, BPRC, IRTA-CReSA and Helmholtz Centre for Infection Research Clinical Trial Support)
- ECRIN (European Clinical Research Infrastructure Network)
- Regulatory support (EATRIS and European Vaccine Initiative)
ALBA Synchrotron: Rapid access to beamlines
ALBA Synchrotron assigns high priority to the projects related to the SARS-CoV-2 virus. The operations have stopped until 25 April, but the call is open, the proposals will be processed, and beam time will be provided as soon as it will be available. A “COVID-19 Rapid Access” call has been established, valid through the year 2020. Quick peer and safety review will be applied to the received proposals.
BNC: Rapid access to neutron beam time
Budapest Neutron Centre (BNC) announced that the beamline proposal deadline for the 2020 autumn cycles has been postponed until 15 May. However, rapid access proposals are still being accepted, where priority access will be given to projects related to the fight against the CoVid-19 pandemic. Email communication of the users with the BNC user office and with the instrument staff is encouraged via addresses available on the BNC website. The reactor is presently scheduled to restart on 11 May, and priority measurements will be performed as the actual state regulations allow the staff, users and reactor to be back in operation.
BSL3: Access to high containment lab facilities
The BSL3 in Rotterdam, was founded to accommodate safe research on infectious diseases, such as COVID-19. The BSL3 research lab facility in Rotterdam was designed to operate according to the highest international biosafety and biosecurity standards, and to facilitate research to multiple teams simultaneously, thus providing unique opportunities for collaborative COVID-19 research using a variety of research modalities including high end instruments for experiments and analyses, in vivo (animals) and in vitro.
CATPRO: Experimental chemical facilities
CATPRO (Efficient Use of Energy Resources Using Catalytic Processes), a research infrastructure newly built within the UniCRE research and development centre, is focused on experimental chemistry with specialization on transfer of laboratory scientific research to industry. Implementation measures are using sophisticated pilot and test equipment. CATPRO has the potential, in the context of the events that are happening regarding the spread of Covid-19, to contribute to the use of experimental research pilot chemical facilities in developing means to mitigate the Covid-19 outbreak.
CCP: Priority access to Covid-19 research projects
Czech Centre for Phenogenomics (CCP) generates rodent models related to diagnosis, treatment and prevention of the Covid-19 virus infection (e.g. several serine protease mouse mutant lines). Available resources, services and support include generation of rodent disease models relevant for Covid-19 research, standard cryopreservation and archiving services, advanced secondary phenotyping pipelines relevant to lung inflammation and fibrosis, pre-clinical testing, metabolomics and MALDI imaging from tissue samples and biopsies. Project proposals can be submitted by email, and will be evaluated and conducted with the highest priority.
CIEMAT-PSA: Facilities for water analysis and disinfection
The Plataforma Solar de Almería (PSA), a dependency of CIEMAT, incorporates a fully equipped laboratory of water sample analysis, with a microbiology laboratory specialized in water disinfection provided also with DNA analysis by Real time PCR. The CIEMAT-PSA is not operating at this moment, however it will be in a short notice.
CIISB: Priority access to structural biology services
CIISB (Czech Infrastructure for Integrative Structural Biology) offers priority access to research groups, which need to use the CIISB structural biology services for R&D projects directly related to the studies of the SARS-CoV-2 virus and projects aiming to develop an effective vaccine and/or treatment of Covid-19 disease. To request the priority access, please submit the research proposal with "COVID-19" in the title through the online application system. Successfully accepted proposals will be free of charge, and no financial contribution will be requested for the measurement and provided services.
CNH2: Rapid access to facilities for PPE production
In response to the COVID-19 pandemic, the National Hydrogen Centre (CNH2) provides rapid access to laboratories and services, such as laser cutting machines, 3D printers and machining centres. Moreover, CNH2 has already produced more than 1 ton of hydrogel and 150 masks for local distribution. Relevant proposals and requests can be submitted via email, through the dedicated webpage (Spanish).
CRESCO6: Free access to high-performance computers
The Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), in order to contribute to research on COVID-19, makes its high-performance computing infrastructure HPC CRESCO6 available - free-of-charge access - to the entire scientific community involved in research activities and application projects for the coronavirus emergency.
CZ-OPENSCREEN: Coronavirus sample testing and database
The National Infrastructure for Chemical Biology (CZ-OPENSCREEN), Czech node to EU-OPENSCREEN ERIC, hosted by the Institute of Molecular Genetics of the Czech Academy of Sciences, plans to test up to 1,000 samples per day. CZ-OPENSCREEN focuses on the identification of new molecular probes and tools for research and validation of compounds suitable for the development of new drugs. The team has also developed the internal database CORONAbase, to register samples and to transform all the appropriate personal data to an electronic version. CZ-OPENSCREEN is sharing the know-how of high-throughput workflow for RNA isolation and preparation of RT-qPCR reactions, as well as the CORONAbase, with other academic institutions involved in Covid-19 testing, in order to improve their testing services and standards.
Czech BioImaging: Open Access support
In response to the COVID-19 pandemic, the National Research Infrastructure for Biological and Medical Imaging (Czech-BioImaging), as the Czech national node to the Euro-BioImaging ERIC pan-European network, offers prioritised access to Czech-BioImaging facilities with no fees attached for COVID-19 relevant scientific projects, selected for implementation within the ongoing call for the Czech-BioImaging Open Access support (July 2020 – June 2021). Deadline for submitting applications is 30th April 2020. More information and the application rules can be found at Czech-BioImaging website.
CzechNanoLab: Nanostructures and nanomaterials services
CzechNanoLab provides open access to the equipment and services in nanotechnology and materials science. The services provided include testing of personal protective equipment (PPE) made of nanomaterials, e.g. analysis of nanofibre filters, chemical analysis of active nanoparticles etc. CzechNanoLab capacities are also offered for the synthesis of magnetic beads used in tests for SARS-CoV-2 presence. Moreover, a priority cost-free access for projects directly related to the research of SARS-CoV-2 coronavirus (e.g. development of microfluidic chips for RNA sequencing)will be provided. CzechNanoLab consists of two sites, the CEITEC Nano Research Infrastructure (Brno), and the Laboratory of Nanostructures and Nanomaterials (LNSM, Prague).
CzechNanoLab is involved in pan-European research infrastructure EuroNanoLab, which is focused on nanofabrication technologies.
CZECRIN: support for COVID-19 clinical studies
The Czech National Node to the European Clinical Research Infrastructure Network (CZECRIN) offers its support, services and expertise to all research-oriented physicians, with the aim of involving its forces in quick access to initiate national and especially transnational clinical trials. CZECRIN launched a dedicated website (available in Czech), to inform not only the professional, but also the non-expert public, about all ongoing and planned activities towards clinical research. Moreover, the NATIONAL CTUs NETWORK, a unit of CZECRIN, has been mapping the interest of healthcare facilities participating in the individual clinical trials focusing on the treatment of patients with the COVID-19 disease, which can be found on this website. In addition, the RI initiated the international study CZECRIN COVID-19, in collaboration with the Slovak SLOVACRIN network, aimed at evaluating the efficacy and safety of the combination of hydroxychloroquine and azithromycin in hospitalized patients with acute respiratory impairment requiring oxygen therapy. Furthermore, CZECRIN will offer research capacity and administrative support to other facilities to battle COVID-19.
DeiC: Data storage and cloud resources
With the current COVID-19 situation, there is need for international cooperation on sharing information and making data available to research that that can contribute to alleviate the impacts of COVID-19 on citizens, healthcare systems and society. The University of Copenhagen/The Technical University of Denmark can make cloud resources, data storage space, etc. available as a flexible secure private cloud setup at Computerome. This also includes a data-lake facility, which can handle different data sets and types and the required storage space. This includes epidemiological information and sequencing data.
e-INFRA CZ: Data and computation services
In the light of the current events regarding the spread of new strain of coronavirus SARS-CoV-2 and Covid-19 disease, Czech e-infrastructure e-INFRA CZ offers priority access to resources and services for projects focused on mitigating the pandemic spread. For these purposes, e-INFRA CZ offers services and knowledge in the areas of remote collaboration, computation, data storage, and computer networking.
ELECMI: Rapid access to microscopy facilities
In the context of COVID-19 pandemic, the Integrated Infrastructure for Electron Microscopy of Materials (ELECMI) provides rapid access to various instruments (HRTEM, including STEM, SEM, Cryogenic Dual Beam instrument, and associated techniques) for studies on materials characterisation, such as the analysis of textiles for Personal Protective Equipment or particles from filters.
ELI Beamlines: Fast track access for coronavirus-related research
The Extreme Light Infrastructure (ELI Beamlines) offers rapid access to the experimental cluster for advanced ultrafast optical spectroscopy and X-ray diffraction, to support the investigation of the SARS-CoV-2 virus characteristics and the development of possible vaccine and treatments. More information about the ELI Beamlines scientific cluster can be found here. Proposals and experiments will be supported by Research Programme 4 for Applications in Molecular, Bio-medical and Material Science, jointly with the ELIBIO Project teams. More information on available support (bio and bio-chemical) labs is available here.
ELIXIR-CZ: Life science data services
The Czech National Infrastructure for Biological Data (ELIXIR-CZ) provides a research infrastructure for the storage, processing and analysing data in the field of life sciences. ELIXIR-CZ has launched a website dedicated to COVID-19, where experts and the general public can find information on activities related to the fight against COVID-19. The website provides recommendations for data storage and sharing and the information on access to relevant data. ELIXIR-CZ specifically provides assistance in setting up the FAIR data principles, special software and analytics tools, and computing resources to help analyse data sets.
Fablab Mons: Free protective visors for medical staff
In coordination with the FabLabs of Wallonia, the FabLab Mons has been involved since the beginning of the epidemic in the development and production of solutions to fight Covid-19 and thus help healthcare professionals who are on the front line. More than 6,000 of protective visors have been produced to date and are intended for the medical professionals, firemen, policemen etc. The aim of these visors is to extend the life of the masks by avoiding projections. This project is possible with the help of volunteers and the support of UMONS, Fund for Medical Research in Hainaut (FRMH) and the FEDER.
GENCI: High performance computing and storage facilites
GENCI, the French HPC agency, is providing its HPC (high performance computing) and storage facilites (located into 3 national centers: TGCC for CEA, IDRIS for CNRS and CINES for French Universities), as well as the user support resources to researchers from academia and industry working on COVID-19. Such supercomputers are used to accelerate modelisation/simulation workloads, post-processing of massive amount of data and use at scale of artificial intelligence. Already 15 projects have been benefited from such fast track, in the fields of massive docking, development of vaccines and therapies, epidemiological research on the spread of the virus, and related applications.
GenomePT: NGS methods to monitor COVID-19
GenomePortugal is a distributed genome sequencing and analysis Research Infrastructure for basic/applied genome research and advanced services, which congregates researchers and technical personnel from 11 national research centers and has the technological capacity and expertise to sequence and analyze complex genomes. GenomePT is engaged in the development of NGS methods to monitor the COVID-19 pandemic and sequence the SARS-Cov-2 genome at the population level to identify new mutations and determine the penetrance of specific viral strains in the population. GenomePT welcomes collaboration requests from European partners in these endeavors, and is keen to share data, protocols and materials to support the fight against COVID-19.
GSI/FAIR researchers in the battle against COVID-19
The GSI Helmholtzzentrum für Schwerionenforschung and the Facility for Antiproton and Ion Research (GSI/FAIR) develops innovative research strategies to support the fight against the current COVID-19 pandemic. The Biophysics Department plans to inactivate the virus with high-energy heavy ions in order to develop vaccines in cooperation with the Helmholtz Centre for Infection Research (HZI). In addition, the therapeutic effect of low-dose radiation against pneumonia caused by SARS-CoV-2 is currently being investigated. The Materials Research Department is working on membranes made of nanopores for improved and fast virus detection and for the development of tailored membranes for viral filtration masks.
Health-RI: Dutch Research Data Support Programme
Health-RI, the Dutch national initiative to facilitate and stimulate an integrated health data infrastructure, launched the Dutch Covid-19 Research Data Support Programme, to support investigators and health care professionals with tools and services in their search for ways to overcome the pandemic and its health consequences. It will do so by connecting communities, providing data services and tools and presenting an overview of COVID-19 related initiatives.
INCDSB: Biomedical services for COVID-19 testing
The PCR-RT capabilities of the Romanian National Institute for Biological Sciences (INCDSB) - member of the ESFRI Consortium DANUBIUS-RI - as part of the global efforts to fight against COVID -19, has made available the services for the Coronavirus testing and is now very actively cooperating with the Romanian Government in the testing campaign at national level. INCDSB is actively supporting Romanian Government with trained personnel, logistics and infrastructure (several devices and a laboratory of cell cultures with expertise in cytotoxicity testing of medical devices).
INCT: Insights in radiation sterilization
With the unprecedented pressure on the supply of PPE, medical devices and laboratory supplies created by the COVID19 pandemic, radiation sterilization is now investigated as a possibility. The Institute of Nuclear Chemistry and Technology (INCT) operates six electron accelerators in the frame of the RAPID infrastructure, which includes one installation designed for R&D and mass sterilization of a wide range of disposable medical devices, including personal protective equipment (PPE) and tissue allografts. INCT is studying a case with national sanitary authorities to find effective methods of dealing with currently threatening Sars-Cov-2 and other pathogens that may appear in the future. Coronaviruses are RNA viruses very sensitive to ionizing radiation and can be deactivated by electron beam, X-rays or gamma rays, but the data for COVID-19 are still not sufficient. The global actions and joined research are needed to gain knowledge of all aspects of emerging disease, thus all comments or information about similar activities are welcome (contact Prof. Chmielewski via email).
IRTA-CReSA: Preclinical research facilities
IRTA-CReSA is a public research institute devoted to research in animal health following the One Health concept. In the context of COVID-19 crisis, the BSL3 large animal and laboratory facilities can support SARS-CoV-2 isolation, in vitro studies of anti-viral and antibody efficacy, in vivo studies of anti-viral, antibody and vaccine efficacy (once hACE2 transgenic mice become available), antiviral, antibody and vaccine research, and animal infection model development.
ISIS: Rapid access upon re-opening
Building on detailed atomic structural information from the research community,nthe application of neutron techniques is capable of providing unique insights, particularly in relation to the fundamental understanding and benchmarking of COVID-19 diagnosis and therapeutics development stages. The ISIS Neutron & Muon Source has rapid and flexible access mechanisms in operation routinely which will enable to these research tools and capabilities to be available for the international research effort upon the earliest resumption of operations.
IT4Innovations: Access to computational resources
IT4Innovations National Supercomputing Centre at VŠB – Technical University of Ostrava has offered its users from academic institutions priority access to its computational resources to solve problems regarding the Covid-19 disease research. Applicants focused on mitigating the coronavirus spread may submit the project proposals within the "Director’s Discretion scheme". Applications will be approved immediately and given significantly higher priority to use the IT4Innovations computational resources.
JCNS: Rapid access to beam time
In order to contribute to the research on the corona virus SARS-CoV-2, JCNS has decided to offer its instruments via a special proposal round with privileged access, giving them priority over all other applications for beam time. All interested scientists are kindly invited to submit their experiment proposal to the JCNS User Office per email without any pre-defined template and without any deadline. Submitted proposals will be assessed as soon as possible to ensure access to the instrument during the next reactor cycle planned between May 5 and June 3, 2020.
KM3NeT-LNS: Functional testing of fabrics for PPE
The hosting laboratory of the KM3NeT Infrastructure"Laboratori Nazionali del Sud" (LNS) of INFN, in collaboration with the University of Catania, has realized a laboratory for the verification of the functional qualities of fabrics intended for the manufacture of masks and other Personal Protective Equipment (PPE) for the prevention of contagion in the COVID-19 emergency. The ANTI_COVID-LAB laboratory will provide technical-scientific assistance to companies that may request to test fabrics to make masks and other medical devices according to the standards set by current regulations, by performing the characterization of the materials, their morphological analysis and will study the capability of the tissues to prevent the virus diffusion.
LAPP: MUST data centre computational and storage capacities
The Particle Physics Laboratory of Annecy (LAPP), a joint research unit of CNRS and Savoie Mont-Blanc University, provides all the possible computational and storage support to the CNRS biologists with its MUST data centre, to contribute in the battle against the COVID-19 pandemic. Exceptionally, LAPP will offer special access to its MUST data centre for important insights into the behaviour of the virus. The computing power of MUST will be used for in-silico screening to select from a database of several million molecules, those that meet very precise specifications and that could attack some major COVID-19 enzymes responsible for the replication of the virus RNA in the human host cell.
LINDAT/CLARIAH-CZ: Computing cluster capacities
LINDAT/CLARIAH-CZ and its host institution – the Institute of Formal and Applied Linguistics at the Faculty of Mathematics and Physics, Charles University, Prague – offers its computing cluster capacity for research computation devoted to fight the SARS-CoV-2 coronavirus and Covid-19 disease, in the amount of ~1000 CPUs, for the period of three months, starting 1st April 2020. More information on how to apply for an account and quota on the cluster, plus a technical description of the capabilities of the cluster, how to run jobs, transfer data etc., can be found here. Please note that decisions to allow access will be made at the discretion of the research infrastructure management and mainly on first-come first-serve basis if fulfilling the above criteria.
LINDAT/CLARIAH-CZ is a joint distributed Czech national node of the pan-European CLARIN ERIC (Common Language Resources and Technology Infrastructure) and DARIAH ERIC (Digital Research Infrastructure for the Arts and Humanities) networks.
LINDAT/CLARIAH-CZ: Natural language Processing services
LINDAT/CLARIAH-CZ and its host institution – the Institute of Formal and Applied Linguistics at the Faculty of Mathematics and Physics, Charles University, Prague - offers access to the Natural Language Processing services, for research devoted to fight the SARS-CoV-2 coronavirus and Covid-19 disease, for a time span of three months, starting 1st April 2020. Most of these services can be accessed through a REST API, without any authentication and/or authorization. The APIs allow to use the NLP tools directly from code or scripts, automating tasks such as analysis of social media posts in 80+ languages (cf. the tool "UDPipe"), translation to and from English to and from several EU languages and similar services.
LINDAT/CLARIAH-CZ is a joint distributed Czech national node of the pan-European CLARIN ERIC (Common Language Resources and Technology Infrastructure) and DARIAH ERIC (Digital Research Infrastructure for the Arts and Humanities) networks.
LIR: Research on COVID-19 impact on mental health
The Leibniz Institute for Resilience Research (LIR) provides a wide range resources and information about how to psychologically deal with the COVID-19 pandemic and how to stay mentally healthy, and participates in number of relative research studies. Amongst them, the large multilingual study DynaCORE-C and its longitudinal arm DynaCORE-L, which examine the psychological responses to the COVID-19 pandemic using anonymous online surveys. Other related studies, available only in German, include LORA-COVID, COSMO-Panel, COVID-19-Intensiv, and the upcoming online-training study Auf Kurs Bleiben (Stay on track).
MIRRI: Active development of diagnostic tests
The Microbial Research Resource Infrastructure (MIRRI) covers different European Biological Resource Centres. Within the French node of MIRRI, one of the units of the Centre de Resources Biologiques de l'Institut Pasteur (CRBIP), namely the biobank of human samples (ICAReB), is actively working in relation to the SARS-CoV2 outbreak. They are receiving hundreds of blood samples per day from different geographical areas and institutions in France. These samples are prepared, cryopreserved and distributed to Pasteurian researchers developing novel diagnostic tests, specifically serological tests.
MLZ: Rapid access to measurements with neutrons
Researchers worldwide are trying to develop drugs or a vaccine against the coronavirus SARS-CoV-2. In view of the corona pandemic, the Heinz Maier-Leibnitz Zentrum (MLZ) offers special access to measurements with neutrons, which can provide important insights into the behaviour of the virus. Scientists who want to use neutrons to study the corona virus SARS-CoV-2 or the disease COVID-19 will have special and privileged access, and do not have to apply for measurement time through the usual channels. Guest scientists should contact the user office directly with their applications for measurement time. A scientific evaluation of the application will then take place as soon as possible.
NANBIOSIS: Rapid access for biomedical product development
The Infrastructure for the Production and Characterization of Nanomaterials, Biomaterials and Systems in Biomedicine (NANBIOSIS) provides rapid access for COVID-19 research. It offers preclinical stages services of biomedical product development. Specifically, synthesis and preparation of biomolecules like antibodies, peptides, recombinant proteins, oligonucleotides for diagnostic, therapeutic and prophylactic purposes.
ODISSEI: Research on COVID-19 social impact
The Open Data Infrastructure for Social Science and Economic Innovations Dutch (ODISSEI) brings together researchers with the necessary data, expertise and resources to conduct ground-breaking research and embrace the computational turn in social enquiry. In response to the COVID-19 pandemic, ODISSEI has granted two data proposals, by awarding time on the LISS data panel for corona-related research into home-schooling (Dr. Thijs Bol, University of Amsterdam) and the distribution of care responsibilities (Dr. Mara A. Yerkes, Utrecht University).
PSI-SLS: Priority access to beamtime
Following the Swiss and international recommendations to slow down the spread of the COVID-19 disease, Paul Scherrer Institute (PSI) is in limited operation until April 19. Swiss Light Source (SLS) is in limited operation and offers Priority access call for work on combating COVID-19.
RECETOX: Virtual drug screening software
RECETOX RI supports the Government of Czechia in managing the pandemic outbreak of Covid-19 by analysing, interpreting and modelling the available population data needed for development of population-protecting strategies and IT tools. RECETOX RI is also fighting the pandemic outbreak of Covid-19 by the virtual screening. The in-house software tool CaverDock can be applied for virtual screening of potential drugs against protein targets identified in the context of coronavirus pandemic. CaverDock has been developed during the last four years and is publicly available via the website.
SIB: Bioinformatics data services and analysis tools
The SIB Swiss Institute for Bioinformatics, Swiss node of ELIXIR and a partner of EMBL-EBI, undertakes a wide range of initiatives against SARS-Cov-2, providing data services and analysis tools that can help researchers answer the following questions:
- From where did the new coronavirus arise, and how did it move to humans?
- How is it spreading and evolving?
- How can we develop therapies to treat it?
SSH COVID-19: A portal for Dutch Social Sciences and Humanities
The SSH COVID-19 portal, the expert portal for Dutch Social Sciences and Humanities, aims to consolidate and organize the SSH expertise across the Dutch universities in a publicly available national portal, ensuring fast and direct access to academic experts.
Web-Survey: Living and Working in Coronavirus Times
The WageIndicator Foundation, a CLARIN ERIC collaborator, has launched a web survey "Living and Working in Coronavirus Times" in 140 countries in the national languages of these countries to discover what the Corona virus lockdown makes easier or tougher, and how the COVID-19 affects people's jobs, lives and mood. The data of the survey is freely available for non-commercial research, at the IDSC Research Data Center of IZA - Institute of Labor Economics, Bonn.